Review Article

Is Pulp Inflammation a Prerequisite for Pulp Healing and Regeneration?

Table 1

The comparison of cellular events between apoptosis, pyroptosis, and oncosis.

ā€‰ApoptosisPyroptosisOncosis

InitiatingProgrammedProgrammedNonprogrammed,
accidental
Signaling pathwayCaspase-3/6/7, DNA fragmentationCaspase-1 DNA fragmentationNoncaspase
Terminal eventNonlytic, plasma membrane blebbingLytic, pore formation, and release of cytokinesLytic
Effect on tissueNoninflammatory, formation of apoptotic bodiesInflammatoryInflammatory
Cell typesAllMacrophages and DCsAll