Mediators of Inflammation / 2015 / Article / Tab 4

Research Article

Comprehensive Screening of Gene Function and Networks by DNA Microarray Analysis in Japanese Patients with Idiopathic Portal Hypertension

Table 4

Top 25 diseases associated with IPH in Ingenuity iReport.

NumberDiseaseDEGs valueGenes

1Immunodeficiency6CD28, CXCR4, RASGRP1, ADA, CD79A, IGLL1/IGLL5
2Leprosy5CD28, SLAMF1, TGFB1, CD79A, IGLL1/IGLL5
3Transcytosis of HIV-12CXCR4, CD79A
4Genital tumor150.000101439CXCR4, CDK7, FOLH1, STAP1, MKI67, GPX3, ABCA8, TGFB1, ABCC1, SERPINA5, CD44, EDNRA, PTGER2, TNFRSF11B, PEG3
5Agammaglobulinemia20.000135709CD79A, IGLL1/IGLL5
6Metastasis of tumor50.000161747CD28, TGFB1, CXCR4, CD44, PTGER2
7Digestive organ tumor200.000177474ERAP2, HIST1H4A, CXCR4, CDK7, PTTG1, FOLH1, TPD52L1, MELK, MKI67, IGLL1/IGLL5, GPX3, TGFB1, OIT3, ABCC1, C7, E2F5, CD44, MMP12, PEG3, TNFRSF11B
8Colorectal cancer140.000211188ERAP2, HIST1H4A, CXCR4, PTTG1, CDK7, FOLH1, TPD52L1, MELK, MKI67, GPX3, TGFB1, CD44, TNFRSF11B, PEG3
9Tuberculoid leprosy30.000255384CD28, SLAMF1, CD79A
10Metastasis100.000432136CD28, ERAP2, TGFB1, CXCR4, PTTG1, CD44, MLLT4, PTGER2, PEG3, TNFRSF11B
11Granulocyte colony stimulating factor-induced psoriasiform dermatitis20.000470563TGFB1, MKI67
12Rectum cancer30.0005718GPX3, CD44, MKI67
13Vascular disease110.00075445NPR3, SERPINA5, MARC1, TGFB1, EDNRA, PTGER2, CD44, MMP12, CD28, MKI67, CXCR4
14Infection by bacteria80.00090366CD28, SLAMF1, TGFB1, SERPINA5, CD44, MMP12, CD79A, IGLL1/IGLL5
15Replication of HIV-140.00121203CD28, TGFB1, CXCR4, PLA2G10
16Pulmonary hypertension30.001305595NPR3, CXCR4, EDNRA
17Prostatic tumor90.001615688GPX3, TGFB1, CXCR4, FOLH1, CD44, EDNRA, STAP1, MKI67, TNFRSF11B
18Uterine serous papillary cancer60.001802487ABCA8, P2RY14, PTTG1, C7, EDNRA, PEG3
19Fibrosis of lung50.001814056TGFB1, PLA2G10, ADA, EDNRA, MMP12
20Cancer330.001947463ERAP2, HIST2H2BE, PTTG1, FOLH1, TPD52L1, MLLT4, MELK, MKI67, CD79A, IGLL1/IGLL5, GPX3, CD28, SARNP, TGFB1, ABCC1, C7, E2F5, ADA, MMP12, TNFRSF11B, PEG3, HIST1H4A, CXCR4, CDK7, STAP1, ABCA8, P2RY14, RASGRP1, OIT3, SERPINA5, CD44, EDNRA, PTGER2
21Endometrial carcinoma80.002077475GPX3, ABCA8, P2RY14, TGFB1, PTTG1, C7, EDNRA, PEG3
22Neuroblastoma30.002212756CXCR4, ABCC1, CD44
23Edema of tissue20.002294982TGFB1, SPRED2
24Carcinoma280.002351502ERAP2, HIST2H2BE, PTTG1, FOLH1, TPD52L1, MELK, MKI67, IGLL1/IGLL5, GPX3, TGFB1, ABCC1, C7, E2F5, MMP12, TNFRSF11B, PEG3, HIST1H4A, CXCR4, CDK7, STAP1, ABCA8, P2RY14, RASGRP1, OIT3, SERPINA5, CD44, EDNRA, PTGER2
25Polyuria30.002583567NPR3, PTTG1, ABCC1

Underlined genes indicate increases in expression. Not underlined genes indicate decreases in expression.
DEGs: differentially expressed genes.