Decreased Regulatory T Cells in Vulnerable Atherosclerotic Lesions: Imbalance between Pro- and Anti-Inflammatory Cells in Atherosclerosis

Figure 2

Emergence of myeloid DCs in atherosclerotic plaques. (a) Immunohistochemical staining of fascin+ mDCs of a control vessel and of the plaque shoulder regions of a stable and an unstable plaque (200x). The pie diagrams demonstrate the percentage of immunostained cells present in different plaque regions (LC—lipid core, PS—plaque shoulders, FC—fibrous cap, M—media, and CW—contralateral wall). (b) Mean DC number of control vessels (), stable (), and unstable () plaques. Results are expressed as cells per 0.1 mm². Values are presented as median (25–75% CI), , (mDCs—myeloid DCs, pDCs—plasmacytoid DCs).

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