Mediators of Inflammation / 2015 / Article / Fig 1

Research Article

Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE2 Synthesis of HBx(+) Hepatocytes

Figure 1

Effect of caffeine on hepatocyte proliferation and synthesis of PGE2. ((a) and (b)) Cell proliferation at different caffeine concentrations (0, 200, 400, and 800 μM) and different caffeine treatment days (1, 4, and 7 days). The group data represent the mean ± SD (); denotes a statistically significant difference (); # denotes a statistically significant difference (). ((c) and (d)) PGE2 level in the supernatant of different cells in caffeine treatment (800 μM) for 7 days. The group data represent the mean ± SD (); denotes a statistically significant difference (); # denotes a statistically significant difference ().
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