Analysis of Th17 and Tc17 Frequencies and Antiviral Defenses in Gut-Associated Lymphoid Tissue of Chronic HIV-1 Positive Patients
Table 1
Th17 and Th1 frequencies in peripheral blood and gut-associated lymphoid tissue (GALT) samples collected from HIV-1-infected patients () who achieved virological suppression in response to ART therapy.
Frequencies
GALT
Peripheral blood
values
Th17 cells (median/range)
1.06/0.21–3.66
0.26/0.00–0.67
Th1 cells (median/range)
5.71/0.23–25.19
0.16/0.01–28.72
CD4+ DP T cells (median/range)
0.17/0.0–2.28
0.005/0.0–0.12
Naïve Th17 cells (median/range)
1.19/0.0–8.73
0.09/0.0–0.36
Naïve Th1 cells (median/range)
1.01/0.23–11.56
0.04/0.0–13.0
Naïve CD4+ DP T cells (median/range)
0.0/0.0–0.49
0.0/0.0–0.05
Central memory Th17 cells (median/range)
0.935/0.0–3.87
0.24/0.00–1.19
Central memory Th1 cells (median/range)
7.65/0.19–33.14
0.22/0.0–36.21
Central memory CD4+ DP T cells (median/range)
0.15/0.0–3.15
0.01/0.0–0.14
Effector memory Th17 cells (median/range)
0.48/0.0–4.05
0.21/0.00–1.61
Effector memory Th1 cells (median/range)
3.28/0.00–19.53
0.33/0.0–47.04
Effector memory CD4+ DP T cells (median/range)
0.16/0.0–2.03
0.0/0.0–0.34
Wilcoxon test for paired samples was used to compare Th17 and Th1 frequencies in peripheral blood and GALT. Significant values are highlighted in bold.
