Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

Table 1

Patient characteristics.

	Cystic fibrosis	Healthy controls
Number total	80	10
Age (years)	22 ± 10	28 ± 8
Gender (M : F)	48/32	6/4
FEV1 (% pred)	64.6 ± 15	n.d.
FVC (% of pred)	73 ± 20	n.d.
(% pred)	33 ± 12	n.d.
Neutrophils (%) in sputum	88 ± 29	20 ± 9
dF508 homozygous/heterozygous/other	38/27/15	n.d.

Statistical analysis was performed with ANOVA and the two-sided t-test. M: male, F: female; FEV₁: forced expiratory volume in 1 second (% of predicted); results are expressed as means ± standard deviation; n.d. not determined.