Lactoferrin: A Modulator for Immunity against Tuberculosis Related Granulomatous Pathology

Figure 1

Mechanisms of TDM-induced granulomas. Cytokines and immune-regulatory factors induced by mycobacterial glycolipid TDM play key roles in the development of pathology induced during mycobacterial infection. Model systems using isolated TDM allow identification of host immune function to extrapolate findings of immune related pathology occurring during clinical manifestation of tuberculosis disease [17, 33, 37, 38, 41, 52–58].