Research Article

Pegylated Interferon- Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat

Table 4

Mean ± SD of serum and liver concentrations of activin-A and follistatin in the different groups.

Activin-A (pg/mL)Follistatin (pg/mL)
SerumLiverSerumLiver

Control166.5 ± 41.7216.1 ± 45.7128.9 ± 40.972.6 ± 22.1
Peg-only92.08 ± 15.3a115.2 ± 37.5a354.15 ± 91.1a157.4 ± 28.5a
Peg & RBV 56.5 ± 10.9a,b112.4 ± 41.6a212.4 ± 40.4a,b134.4 ± 38.6a
RBV-only174.7 ± 35.8b,c281.8 ± 84.2b,c98.9 ± 33.4b,c82.2 ± 23.5b,c

compared to control, b compared to Peg-only, and c compared to Peg & RBV group.