Clinical Trial and In Vitro Study for the Role of Cartilage and Synovia in Acute Articular Infection

Table 1

Comparison of patients with arthroplasty and normal joints using epidemiological and inflammatory parameters. The first data set shows the comparisons for all patients, the second for the subgroup of patients with exclusive knee infections  and knee arthroplasties. m: male, f: female, ASA: physical status according to the American Society of Anesthesiologists, ICU: intensive care unit, y: yes, n: no, and CRP: C-reactive protein in serum. Aspin-Welch test, ⁺Chi square test, -test (Mann-Whitney), and -test.

	Endoprosthesis ()	Normal joint ()
All patients
Age (years)	71.3 ± 3.4	58.3 ± 2.8	0.001
Gender (m/f)	7/1	44/24	n.s.^+
ASA classification	3.0 ± 0.2	2.2 ± 0.1	0.01^#
Body mass index	31.6 ± 1.6	27.3 ± 0.8	0.03^#
ICU treatment (y/n)	6/2	16/52	0.002^+
Initial leucocyte count (Tsd/µL)	13.7 ± 1.9	10.9 ± 0.6	n.s.^++
Initial CRP (mg/L)	154.9 ± 38.1	112.2 ± 10.8	n.s.^++
	Endoprosthesis ()	Normal joint ()
Subgroup with exclusive knee infections
Age (years)	69.1 ± 4.2	55.9 ± 3.3	n.s.
Gender (m/f)	5/1	37/14	n.s.^+
ASA classification	3.0 ± 0.3	2.1 ± 0.1	0.02^#
Body mass index	31.6 ± 2.1	27.1 ± 0.9	n.s.^#
ICU treatment (y/n)	4/2	12/39	0.026^+
Initial leucocyte count (Tsd/µL)	13.0 ± 2.5	10.5 ± 0.7	n.s.^++
Initial CRP (mg/L)	151.6 ± 52.9	103.0 ± 11.9	n.s.^++