Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels

Figure 2

Histological features of sham-operated (sham), CRF, and advanced CRF rat kidneys. (a) Hematoxylin and eosin (H&E) and Masson’s trichrome staining, in sham-operated (sham), CRF (8 weeks after nephrectomy), and advanced CRF (14 weeks after nephrectomy) rat kidneys. ((A), (B), and (C)) Low-power views of cortex, Masson’s trichrome. Magnification, ×20. ((D), (E), and (F)) High-power views of cortical interstitium, H&E. Magnification, ×60. (b) Immunofluorescence staining using antibodies for CD3 ((A) green) and ED-1 ((B) green), costained with Ki-67 (red) in advanced CRF rat kidneys. High-power views of the cortical interstitium. Magnification, ×60. Modified from [34].

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