Research Article

MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction

Table 2

Mean echocardiographic parameters at 7 and 28 days after MI.

LVIDd LVIDd LVIDs LVIDs EF EF FS FS
7 days28 days7 days28 days7 days28 days7 days28 days

Sham2.32 ± 0.322.82 ± 0.261.15 ± 0.151.54 ± 0.11 86.6 ± 1.1482.6 ± 2.349.6 ± 1.1445 ± 2.45
Antagomir3.68 ± 0.333.96 ± 0.412.36 ± 0.372.59 ± 0.4272.5 ± 6.1971.0 ± 5.6036.0 ± 4.5535.0 ± 4.2
Control3.6 ± 0.24.07 ± 0.562.5 ± 0.263.04 ± 0.6964.8 ± 6.7653.4 ± 8.7930.8 ± 4.4423.6 ± 4.72

LVIDd: left ventricular internal diameter diastole; LVIDs: left ventricular internal diameter systole; EF: ejection fraction; FS: fractional shortening; compared to controls.