Chemokine-Ligands/Receptors: Multiplayers in Traumatic Spinal Cord Injury

Figure 1

Chemokine classification. Based on the presence of a cysteine motif in the N-terminal region of the protein, chemokines divide into four subgroups (alpha-, beta-, gamma-, and delta-chemokines). Through activation of G-protein coupled chemokine-receptors, these chemotactic proinflammatory mediators are involved in varied pathological and physiological processes.