Role of the Immunogenic and Tolerogenic Subsets of Dendritic Cells in Multiple Sclerosis

Figure 3

Dendritic cells (DCs) promote the differentiation of Th1 and Th17 cells. Mature DCs could induce the differentiation of naive CD4+ T cells into different types of T helper (Th) cells. Both Th1 and Th17 cells play pathogenic roles in the disease progression of MS mainly through their cytokines.