Research Article

Moderate Exercise Training Attenuates the Severity of Experimental Rodent Colitis: The Importance of Crosstalk between Adipose Tissue and Skeletal Muscles

Figure 2

The representative macroscopic appearance of intact colonic mucosa (a) and the colonic mucosa of rat with TNBS colitis fed normal diet (b) or HFD without exercise (c) and HFD with exercise (d) at day 14 after TNBS induction. Note, the normal appearance of colonic mucosa (a) and the severe colonic damage in TNBS rat fed normal diet (b). This damage was exacerbated in untrained rat fed HFD as reflected by necrotic damage occupying larger area of colonic mucosa (c). However, in trained rat fed HFD, the colonic damage was reduced and smaller area of the colonic damage was clearly confirmed by gross inspection (d).
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