Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A<sub>2</sub>, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw

<div>Relative expression of COX-2 mRNA (a), mPGES-1 mRNA (b), and PGIS mRNA (c) in rat hind paw. Carrageenan (Car) injection (filled bars) elevated COX-2 mRNA and mPGES-1 mRNA levels compared to saline (Sal) injection (open bars) though the elevations were not statistically significant by<i> t</i>-test except for COX-2 and PGIS in BEL-treated groups. BEL did not significantly influence COX-2 mRNA, mPGES-1 mRNA, or PGIS mRNA levels.</div>

Mediators of Inflammation

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Figure 3

Figure 3: Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A<sub>2</sub>, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw 

Figure 3 | Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A2, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw 