Review Article

Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut

Figure 1

Components of the mucosal barrier in healthy gut (left) and inflammatory bowel disease (IBD) (right). For explanations see text. The basic structure of tight junctions and other junctional complexes are shown in the bottom-right box. JAM: junctional adhesion molecules.