Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI

Figure 2

Initial KC activation. Initial ROI levels correlated with tissue quality and donor anamnesis. Initial ROI levels were measured in KC cultures by means of the DCF assay performed directly after KC isolation. Data show means ± SEM. : shown in the figure.