Research Article

Prostacyclin Synthase: Upregulation during Renal Development and in Glomerular Disease as well as Its Constitutive Expression in Cultured Human Mesangial Cells

Figure 2

PGIS mRNA localizes to mesangial fields ((a), arrow) and endothelial cells of an interlobar artery ((b), arrow). Expression of PGIS protein and mRNA in normal adult kidney. (c) Low power view shows expression of PGIS in endothelial and smooth muscle cells of an arcuate artery (arrow). (d) shows expression of PGIS in cells of the juxtaglomerular apparatus (arrow), adjacent to the macula densa.
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