Serum IL-6 and IL-23 Levels and Their Correlation with Angiogenic Cytokines and Disease Activity in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome

Table 2

A logistic regression model of the OR of the increased serum level of interleukin-6.

Covariates	Serum IL-6 ≥ 1.53 pg/mL		Serum IL-6 ≥ 6.64 pg/mL
	OR (95% CI)	P	OR (95% CI)	P
Ankylosing spondylitis	2.04 (0.87–4.78)	0.10	1.30 (0.6–2.77)	0.51
Psoriatic arthritis	0.70 (0.32–1.51)	0.36	0.86 (0.40–1.84)	0.69
SAPHO	0.61 (0.23–1.65)	0.33	0.82 (0.28–2.41)	0.72
CRP ≥ 5 mg/L	7.68 (2.93–20.16)	<0.0001	15.76 (4.54–54.66)	<0.0001
BASDAI ≥ 4	2.90 (1.16–7.25)	0.02	1.11 (0.50–2.45)	0.79
NSAIDs	1.15 (0.42–3.11)	0.78	0.58 (0.20–1.65)	0.31
Sulfasalazine	0.64 (0.29–1.39)	0.26	1.07 (0.50–2.28)	0.85
Methotrexate	1.71 (0.71–4.15)	0.23	1.42 (0.65–3.11)	0.38

IL-6: interleukin-6.
OR: odds ratio.
95% CI: 95% confidence interval.
NSAIDs: nonsteroidal anti-inflammatory drugs.