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Mediators of Inflammation
Volume 2015, Article ID 854670, 5 pages
Research Article

A Nomogram to Predict Prognostic Value of Red Cell Distribution Width in Patients with Esophageal Cancer

1Department of Oncological Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China
2Department of Nursing, Zhejiang Cancer Hospital, Hangzhou 310022, China
3Department of Thoracic Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China

Received 23 December 2014; Accepted 31 March 2015

Academic Editor: Sydney C. W. Tang

Copyright © 2015 Gui-Ping Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. The prognostic value of inflammatory index in esophageal cancer (EC) was not established. In the present study, we initially used a nomogram to predict prognostic value of red cell distribution width (RDW) in patients with esophageal squamous cell carcinoma (ESCC). Methods. A total of 277 ESCC patients were included in this retrospective study. Kaplan-Meier method was used to calculate the cancer-specific survival (CSS). A nomogram was established to predict the prognosis for CSS. Results. The mean value of RDW was 14.5 ± 2.3%. The patients were then divided into two groups: RDW ≥ 14.5% and RDW < 14.5%. Patients with RDW < 14.5% had a significantly better 5-year CSS than patients with RDW ≥ 14.5% (43.9% versus 23.3%, P < 0.001). RDW was an independent prognostic factor in patients with ESCC (P = 0.036). A nomogram could be more accurate for CSS. Harrell’s c-index for CSS prediction was 0.68. Conclusion. RDW was a potential prognostic biomarker in patients with ESCC. The nomogram based on CSS could be used as an accurately prognostic prediction for patients with ESCC.