Serum Vitamin A and Inflammatory Markers in Individuals with and without Chronic Obstructive Pulmonary Disease

Table 2

Inflammatory markers in the serum of control subjects and COPD patients.

Variables	Control ( = 50)	COPD ( = 50)	value
TNF-α (pg/mL)	3.9 (3.6–5.4)	4.5 (4.1–5.1)	0.05
IL-6 (pg/mL)	0.3 (0.2–0.6)	1.1 (0.8–1.9)	<0.001
IL-8 (pg/mL)	4.9 (3.4–7.1)	4.1 (3.3–7.2)	0.48
CRP (mg/L)	1.1 (0.6–2.2)	6.3 (2.7–9.3)	<0.001
Neutrophils (cell/mm^3)	3605 (2900–4342)	4712 (4037–5667)	<0.001
Lymphocytes (cell/mm^3)	1750 (1529–2090)	1720 (1470–2397)	0.94
Leukocytes (cell/mm^3)	6400 (5300–7300)	7600 (7000–9125)	<0.001

Data are reported as the median (interquartile range (25–75%)). TNF-α: tumor necrosis factor; IL-6: interleukin-6; IL-8: interleukin-8; CRP: C-reactive protein. The values refer to COPD compared with the control (Mann-Whitney test and chi-square).