The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease

<div>The interaction partners of SLAP-1 (pink) and SLAP-2 (green). Several proteins have been reported to interact with SLAP-1 molecule: c-Cbl, CD3 <i>ζ</i> chain, ECK, EpoR, Ig<i>α</i>, LAT, Lck, PDGFR, SLP-76, Syk, v-abl, Vav (protooncogene vav), ZAP70, c-kit, Flt3, and FLI. SLAP-2 interacts with c-Cbl, CD3 <i>ζ</i> chain, CSFR, and ZAP70.</div>

Mediators of Inflammation

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Figure 2

Figure 2: The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease 