Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2016 (2016), Article ID 1605948, 10 pages
http://dx.doi.org/10.1155/2016/1605948
Research Article

CD97/ADGRE5 Inhibits LPS Induced NF-κB Activation through PPAR-γ Upregulation in Macrophages

Department of Cardiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, China

Received 16 October 2015; Revised 28 December 2015; Accepted 28 December 2015

Academic Editor: Tânia Silvia Fröde

Copyright © 2016 Shuai Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Goerdt and C. E. Orfanos, “Other functions, other genes: alternative activation of antigen- presenting cells,” Immunity, vol. 10, no. 2, pp. 137–142, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Mantovani, A. Sica, S. Sozzani, P. Allavena, A. Vecchi, and M. Locati, “The chemokine system in diverse forms of macrophage activation and polarization,” Trends in Immunology, vol. 25, no. 12, pp. 677–686, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. D. M. Mosser and J. P. Edwards, “Exploring the full spectrum of macrophage activation,” Nature Reviews Immunology, vol. 8, no. 12, pp. 958–969, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. F. O. Martinez, L. Helming, and S. Gordon, “Alternative activation of macrophages: an immunologic functional perspective,” Annual Review of Immunology, vol. 27, pp. 451–483, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. A. J. McKnight and S. Gordon, “EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules,” Immunology Today, vol. 17, no. 6, pp. 283–287, 1996. View at Publisher · View at Google Scholar · View at Scopus
  6. M. J. Kwakkenbos, E. N. Kop, M. Stacey et al., “The EGF-TM7 family: a postgenomic view,” Immunogenetics, vol. 55, no. 10, pp. 655–666, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. J. C. Leemans, A. A. Te Velde, S. Florquin et al., “The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense,” The Journal of Immunology, vol. 172, no. 2, pp. 1125–1131, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. W. Eichler, “CD97 isoform expression in leukocytes,” Journal of Leukocyte Biology, vol. 68, no. 4, pp. 561–567, 2000. View at Google Scholar · View at Scopus
  9. M. J. Kwakkenbos, W. Pouwels, M. Matmati et al., “Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells,” Journal of Leukocyte Biology, vol. 77, no. 1, pp. 112–119, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Veninga, D. M. de Groot, N. McCloskey et al., “CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism,” Journal of Leukocyte Biology, vol. 89, no. 3, pp. 413–421, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Hamann, W. Eichler, D. Hamann et al., “Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain,” The Journal of Immunology, vol. 155, no. 4, pp. 1942–1950, 1995. View at Google Scholar · View at Scopus
  12. W. Eichler, G. Aust, and D. Hamann, “Characterization of an early activation-dependent antigen on lymphocytes defined by the monoclonal antibody BL-Ac(F2),” Scandinavian Journal of Immunology, vol. 39, no. 1, pp. 111–115, 1994. View at Publisher · View at Google Scholar · View at Scopus
  13. L. H. Jaspars, W. Vos, G. Aust, R. A. W. Van Lier, and J. Hamann, “Tissue distribution of the human CD97 EGF-TM7 receptor,” Tissue Antigens, vol. 57, no. 4, pp. 325–331, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Ward, R. Lake, J. J. Yin et al., “LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells,” Cancer Research, vol. 71, no. 23, pp. 7301–7311, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Aust, W. Eichler, S. Laue et al., “CD97: a dedifferentiation marker in human thyroid carcinomas,” Cancer Research, vol. 57, no. 9, pp. 1798–1806, 1997. View at Google Scholar · View at Scopus
  16. M. Steinert, M. Wobus, C. Boltze et al., “Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues,” The American Journal of Pathology, vol. 161, no. 5, pp. 1657–1667, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. M. van Eijk, G. Aust, M. S. M. Brouwer et al., “Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease,” Immunology Letters, vol. 129, no. 2, pp. 64–71, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. E. Wandel, A. Saalbach, D. Sittig, C. Gebhardt, and G. Aust, “Thy-1 (CD90) is an interacting partner for CD97 on activated endothelial cells,” Journal of Immunology, vol. 188, no. 3, pp. 1442–1450, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Tsuruta, Y.-J. Park, G. P. Siegal, G. Liu, and E. Abraham, “Involvement of vitronectin in lipopolysaccaride-induced acute lung injury,” The Journal of Immunology, vol. 179, no. 10, pp. 7079–7086, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. J. L. Swantek, L. Christerson, and M. H. Cobb, “Lipopolysaccharide-induced tumor necrosis factor-α promoter activity is inhibitor of nuclear factor-κB kinase-dependent,” Journal of Biological Chemistry, vol. 274, no. 17, pp. 11667–11671, 1999. View at Publisher · View at Google Scholar · View at Scopus
  21. A. N. Shakhov, M. A. Collart, P. Vassalli, S. A. Nedospasov, and C. V. Jongeneel, “κB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor α gene in primary macrophages,” Journal of Experimental Medicine, vol. 171, no. 1, pp. 35–47, 1990. View at Publisher · View at Google Scholar · View at Scopus
  22. F. A. Ran, P. D. Hsu, J. Wright, V. Agarwala, D. A. Scott, and F. Zhang, “Genome engineering using the CRISPR-Cas9 system,” Nature Protocols, vol. 8, no. 11, pp. 2281–2308, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. A. N. Shakhov, M. A. Collart, P. Vassalli, S. A. Nedospasov, and C. V. Jongeneel, “Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages,” Journal of Experimental Medicine, vol. 171, no. 1, pp. 35–47, 1990. View at Publisher · View at Google Scholar · View at Scopus
  24. J. L. Swantek, L. Christerson, and M. H. Cobb, “Lipopolysaccharide-induced tumor necrosis factor-α promoter activity is inhibitor of nuclear factor-κB kinase-dependent,” The Journal of Biological Chemistry, vol. 274, no. 17, pp. 11667–11671, 1999. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Pang, J. Benicky, J. Wang, M. Orecna, E. Sanchez-Lemus, and J. M. Saavedra, “Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes,” Journal of Hypertension, vol. 30, no. 1, pp. 87–96, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Ao, Y. Huo, L. Qi, Z. Xiong, L. Xue, and Y. Qi, “Pioglitazone suppresses the lipopolysaccharide-induced production of inflammatory factors in mouse macrophages by inactivating NF-κB,” Cell Biology International, vol. 34, no. 7, pp. 723–730, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. J. S. Welch, M. Ricote, T. E. Akiyama, F. J. Gonzalez, and C. K. Glass, “PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 11, pp. 6712–6717, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. B. Lecka-Czernik and L. J. Suva, “Resolving the two ‘bony’ faces of PPAR-γ,” PPAR Research, vol. 2006, Article ID 27489, 9 pages, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Takano, T. Nagai, M. Asakawa et al., “Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes,” Circulation Research, vol. 87, no. 7, pp. 596–602, 2000. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Ricote, A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass, “The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation,” Nature, vol. 391, no. 6662, pp. 79–82, 1998. View at Publisher · View at Google Scholar · View at Scopus
  31. B. Gasz, L. Lenard, L. Benko et al., “Expression of CD97 and adhesion molecules on circulating leukocytes in patients undergoing coronary artery bypass surgery,” European Surgical Research, vol. 37, no. 5, pp. 281–289, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. G.-K. Tan and Y. Tabata, “Chondroitin-6-sulfate attenuates inflammatory responses in murine macrophages via suppression of NF-κB nuclear translocation,” Acta Biomaterialia, vol. 10, no. 6, pp. 2684–2692, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. N. Cañas, R. Gorina, A. M. Planas et al., “Chondroitin sulfate inhibits lipopolysaccharide-induced inflammation in rat astrocytes by preventing nuclear factor κ B activation,” Neuroscience, vol. 167, no. 3, pp. 872–879, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Thieringer, J. E. Fenyk-Melody, C. B. Le Grand et al., “Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo,” The Journal of Immunology, vol. 164, no. 2, pp. 1046–1054, 2000. View at Publisher · View at Google Scholar · View at Scopus
  35. G. Pascual, A. L. Fong, S. Ogawa et al., “A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ,” Nature, vol. 437, no. 7059, pp. 759–763, 2005. View at Publisher · View at Google Scholar · View at Scopus