A Single Bout of Fasting (24 h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats

Table 1

Effects of a 24 h fast on basal markers of energy status and cytokine concentrations in blood plasma. Differences between blood plasma variables in fed (FED + 0IS, ) versus fasted (FASTED + 0IS, ) control rats by unpaired, 2-tailed -test. Values are expressed as means ± SEM.

	FED	FASTED	value	Percent change
Glucose (mg/dL)	123.34 ± 4.67	101.63 ± 2.42	0.001	−17.6%
NEFA (mEq/L)	0.37 ± 0.04	0.57 ± 0.06	0.01	54.1%
Insulin (ng/mL)	1.34 ± 0.18	0.32 ± 0.07	<0.0001	−76.1%
Leptin (pg/mL)	5491.06 ± 1046.82	986.91 ± 114.67	0.001	−82.0%
Corticosterone (ug/dL)	0.49 ± 0.35	7.21 ± 3.31	0.06	1369.4%
TNF-α (pg/mL)	102.73 ± 14.64	54.56 ± 5.85	0.01	−46.8%
IL-1β (pg/mL)	17.16 ± 4.16	5.26 ± 1.62	0.02	−69.3%
IL-6 (pg/mL)	962.13 ± 135.52	502.61 ± 125.88	0.03	−47.8%
IL-10 (pg/mL)	13.93 ± 1.68	6.51 ± 0.75	0.001	−53.3%