Table 1: Effects of a 24 h fast on basal markers of energy status and cytokine concentrations in blood plasma. Differences between blood plasma variables in fed (FED + 0IS, ) versus fasted (FASTED + 0IS, ) control rats by unpaired, 2-tailed -test. Values are expressed as means ± SEM.

FEDFASTED valuePercent change

Glucose (mg/dL)123.34 ± 4.67101.63 ± 2.420.001−17.6%
NEFA (mEq/L)0.37 ± 0.040.57 ± 0.060.0154.1%
Insulin (ng/mL)1.34 ± 0.180.32 ± 0.07<0.0001−76.1%
Leptin (pg/mL)5491.06 ± 1046.82986.91 ± 114.670.001−82.0%
Corticosterone (ug/dL)0.49 ± 0.357.21 ± 3.310.061369.4%
TNF-α (pg/mL)102.73 ± 14.6454.56 ± 5.850.01−46.8%
IL-1β (pg/mL)17.16 ± 4.165.26 ± 1.620.02−69.3%
IL-6 (pg/mL)962.13 ± 135.52502.61 ± 125.880.03−47.8%
IL-10 (pg/mL)13.93 ± 1.686.51 ± 0.750.001−53.3%