Table 2: Effects of a 24 h fast on basal cytokine concentrations in WAT. Differences between WAT cytokines in fed (FED + 0IS, ) versus fasted (FASTED + 0IS, ) control rats by unpaired, 2-tailed -test. Values are expressed as means ± SEM.

FEDFASTED valuePercent change

Subcutaneous WAT
 TNF-α (pg/mg)4.32 ± 0.473.27 ± 0.190.06−24.3%
 IL-1β (pg/mg)10.91 ± 0.76.72 ± 0.770.00138.5%
 IL-6 (pg/mg)2.15 ± 0.131.9 ± 0.030.05−10.7%
 IL-10 (pg/mg)1.01 ± 0.060.75 ± 0.090.0326.7%
 TNF-α/IL-104.4 ± 0.584.67 ± 0.420.726.1%
 IL-1β/IL-1010.99 ± 0.869.55 ± 1.150.34−13.0%
Intraperitoneal WAT
 TNF-α (pg/mg)6.18 ± 0.356.85 ± 0.480.2710.8%
 IL-1β (pg/mg)10.79 ± 1.2810.46 ± 0.980.89−2.1%
 IL-6 (pg/mg)25.65 ± 5.345.85 ± 1.040.00377.1%
 IL-10 (pg/mg)1.02 ± 0.071.02 ± 0.060.98−0.2%
 TNF-α/IL-106.09 ± 0.226.73 ± 0.210.0510.3%
 IL-1β/IL-1010.57 ± 1.1110.39 ± 0.710.89−1.8%
Visceral WAT
 TNF-α (pg/mg)6.1 ± 0.464.05 ± 0.330.00333.6%
 IL-1β (pg/mg)9.78 ± 0.685.68 ± 0.740.00141.8%
 IL-6 (pg/mg)39.12 ± 5.2415.66 ± 5.140.00759.9%
 IL-10 (pg/mg)1.2 ± 0.060.88 ± 0.100.0226.7%
 TNF-α/IL-105.15 ± 0.434.45 ± 0.350.13−17.5%
 IL-1β/IL-108.18 ± 0.505.54 ± 0.520.00332.2%