Research Article
CETP Lowers TLR4 Expression Which Attenuates the Inflammatory Response Induced by LPS and Polymicrobial Sepsis
Figure 9
The presence of CETP reduced the cellular uptake of LPS, TLR4 expression, and NF-κB activation (p65) and consequently decreased the secretion of IL-6 indicating that CETP interferes in TLR4 signaling pathways.