Epidermal Growth Factor and Intestinal Barrier Function

Table 3

Effects of EGF on intestinal bacterial colonization and translocation.

Animals	Significant results	Reference
New Zealand white rabbits	EGF treatment significantly inhibits enteropathogenic Escherichia coli colonization in the small and large intestine	[27]
Newborn rabbits	Administration of EGF significantly reduced bacterial translocation and was associated with increased goblet cells in intestine	[59]
Rats	Administration of EGF significantly reduced aerobic bacterial colonization	[60]
White leghorn chicks	EGF reduced Campylobacter jejuni colonization in the jejunum and dissemination to the liver and spleen and inhibited Escherichia coli translocation	[30]
Rats	An intervention with EGF decreased fecal Escherichia coli colonization	[8]
Early-weaned piglets	EGF treatment decreased the amount of Escherichia coli in the ileum and cecum and Enterococcus counts in the ileum	[21]