Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema

Table 3

Inflammatory markers and physiologic parameters of persons developing AMS versus those not developing AMS during acute hypoxic exposure and retrospectively at sea level (normoxia).

	Normoxia			Hypoxia
	No AMS	AMS		No AMS	AMS
Heart rate (1/min)				0.75				0.47
SaO2 (%)			0.70			0.16
PaO2 (kPa)			0.73			0.12
LLS-AMS			0.25			0.001
suPAR (ng/mL)			0.10			0.49
CRP (mg/L)			0.38			0.67
IL-6 (ng/L)			0.84			0.77

Values are given as mean ± SD. SaO₂: oxygen saturated hemoglobin fraction and LLS-AMS: Lake Louise score for acute mountain sickness; the cutoff value for the presence of AMS is defined as LLS-AMS ≥ 5 [29, 30].