Research Article
Diagnostic Accuracy of Five Different Fecal Markers for the Detection of Precancerous and Cancerous Lesions of the Colorectum
Table 3
Sensitivities, specificities, and positive and negative predictive values of the fecal markers.
| Parameters | M2-PK | HB | HB/HP | Calprotectin | MMP-9 |
| Sensitivity | | | | | | Adenoma sized ≥1 cm | 60 | 80 | 80.0 | | | CRC | 94.7 | 94.7 | 100.0 | 77.8 | 72.2 | Adenoma sized ≥1 cm + CRC | 76.9 | 87.2 | 90.9 | | |
| Specificity | | | | | | Adenoma sized ≥1 cm | 67.5 | 72.5 | 52.9 | | | CRC | 67.5 | 72.5 | 52.9 | 70.0 | 95.0 | Adenoma sized ≥1 cm + CRC | 67.5 | 72.5 | 52.9 | | |
| PPV (%) | | | | | | Adenoma sized ≥1 cm | 80 | 59.2 | 42.9 | | | CRC | 85.7 | 62 | 52.9 | 53.8 | 86.6 | Adenoma sized ≥1 cm + CRC | 69.7 | 75.5 | 65.2 | | |
| NPV (%) | | | | | | Adenoma sized ≥1 cm | 77.1 | 96.6 | 85.7 | | | CRC | 96.4 | 96.6 | 100.0 | 87.5 | 88.3 | Adenoma sized ≥1 cm + CRC | 75 | 85.3 | 85.7 | | |
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