The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s Thyroiditis

Table 1

List of TaqMan probes and amplicon sizes of investigated genes.

Assay ID	Gene abbreviation	Gene name	GenBank accession number	Function	Amplicon size (bp)
Hs00428293_m1	ETS1	Erythroblastosis virus E26 oncogene homolog 1 (avian)	NM_001143820.1	Transcription factor, involved in mounting of Th1 response and inhibition of Th17 development	99
Hs01085834_m1	FOXP3	Forkhead box P3	NM_014009.3	Transcriptional regulator of Treg cell development and function	61
Hs00153153_m1	HIF1A	Hypoxia inducible factor 1	NM_001530.3	Transcriptional regulator, activator of ROR-γt expression and Th17 differentiation	76
Hs99999909_m1	HPRT1	Hypoxanthine phosphoribosyltransferase 1	NM_000194.2	Purine metabolism	100
Hs00153357_m1	PRDM1/BLIMP1	PR domain containing 1, with ZNF domain/B-lymphocyte-induced maturation protein 1	NM_001198.3	Repressor of beta-interferon (β-IFN) gene expression	65
Hs00420895_gH	RPLP0	Ribosomal protein, large, P0	NM_001002.3	Ribosomal protein, component of 60S subunit	76
Hs00894392_m1	TBX21	T-box 21	NM_013351.1	T cell-specific T-box transcription factor	119
Hs99999910_m1	TPB	TATA box binding protein	NM_003194.4	Transcription factor	127