Research Article
Interleukin-27 as a Novel Biomarker for Early Cardiopulmonary Failure in Enterovirus 71-Infected Children with Central Nervous System Involvement
Table 1
Summary of clinical data.
| | Groups | EV71-infected patients | Controls () | | Stage II () | Stage III () | Stage IV () |
| | Female/male | 27/28 | 20/22 | 16/14 | 48/47 | | Age (months), mean ± SD | 25.31 ± 10.24 | 26.55 ± 11.23 | 26.21 ± 10.47 | 26.11 ± 11.05 | | High fever (>39°C >3 days at admission), (%) | 33 (60.00) | 25 (59.52) | 20 (66.67) | 0 (0) | | Vomiting, (%) | 15 (27.27) | 13 (30.95) | 13 (43.33) | 0 (0) | | Skin rash, (%) | 52 (94.55) | 40 (95.24) | 29 (96.67) | 0 (0) | | Oral ulcer, (%) | 53 (96.36) | 42 (100) | 29 (96.67) | 0 (0) | | Easily frightened, (%) | 8 (14.55) | 10 (23.81) | 12 (40.00) | 0 (0) | | Depression, (%) | 16 (29.09) | 18 (42.86) | 25 (83.33) | 0 (0) | | Abnormal breathing, (%) | 9 (16.36) | 8 (19.05) | 15 (50.00) | 0 (0) | | Increased heart rate, (%) | 25 (45.45) | 26 (61.90) | 26 (86.67) | 0 (0) | | GLU > 8.3 mmol/L, (%) | 30 (54.55) | 30 (71.43) | 25 (83.33) | 0 (0) | | CRT > 2 s, (%) | 8 (14.55) | 25 (59.52) | 23 (76.67) | 0 (0) | | WBC (×109/L), mean ± SD | 7.08 ± 3.41 | 8.74 ± 3.33 | 11.50 ± 3.37 | 6.78 ± 2.27 |
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WBC: white blood cell.
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