MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations

Figure 1

MMP8 expression is elevated in lesional skin of AI patients. (a) Picture of affected gluteal skin of a 53-year-old patient suffering from AI with inflammatory lesions and fistulas. (b) MMP8 expression was analyzed in biopsies from skin of 8 healthy control donors and the lesional skin of 10 AI and 10 psoriasis patients by RT-qPCR. Mean data ± SEM are shown. Significance of differences was analyzed using the Mann-Whitney U test (two-tailed; ).

(a)

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