Parallel Aspects of the Microenvironment in Cancer and Autoimmune Disease

Table 1

Hypoxia in the microenvironment.

	Cancer tissue	RA (SF)	MS/EAE	SLE
Hypoxia	≤5 mmHg (70–80 m from vessel); ≤0.5 mmHg (≥150 m from vessel); [5]; 0–2.5 mmHg (breast cancer) [6]	18–24 mmHg	9–20 mmHg in EAE [7]	Not directly measured; anemic hypoxia reported [8]
Normal tissue	Range: 25–72 mmHg (depending on tissue) [9]	40–70 mmHg [10–12]	35 mmHg [7]