Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF-β Signal Pathway

Figure 2

Renal fibrosis at 5 weeks after DXR injection in different groups of mice as indicated. (a) Kidney sections were subjected to Masson-trichrome staining; (b) kidney sections expressed the mRNA of α-SMA, and E-cadherin, fibronectin; (c) kidney sections expressed the protein of α-SMA, E-cadherin, and fibronectin; (d) the relative protein expression of fibronectin, α-SMA, and E-cadherin as seen in the kidney sections. The control and DAL treatment groups are compared with the DXR group. Values are statistically significant at ; the DXR group is compared with the control group. Values are statistically significant at .

(a)

(b)

(c)

(d)