Resolvin E1 Inhibits Substance P-Induced Potentiation of TRPV1 in Primary Sensory Neurons

Figure 1

Expression of TRPV1, ChemR23, and NK-1 in a subset of small-sized DRG neurons. (a) Single-cell RT-PCR analysis from 10 individual small-sized DRG neurons showing colocalization of NK-1 with TRPV1 and ChemR23. (b) Expression of TRPV1, ChemR23, and NK-1 by single-cell RT-PCR in dissociated small-sized DRG neurons. (c) A Venn diagram showing the relationship of NK-1⁺, ChemR23⁺, and TRPV1⁺ populations in small-sized dorsal root ganglion (DRG) neurons. Note that all NK-1⁺ neurons also express ChemR23 and TRPV1.

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