The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI) Attenuates Elastase-Induced Emphysema in Mice

Table 3

Absolute values of the morphometric analysis for inflammatory, remodeling, and oxidative stress markers, in the airway walls. The neutrophils, TNF-α, MMP-9, MMP-12, TIMP-1, iNOS, eNOS, and MUC-5 are expressed in positive cells/10⁴ µm². The collagen fiber, elastic fiber, and 8-iso-PGF2α are expressed in percentage (%). , compared with the SAL and SAL-rBbKI groups; , compared with the ELA-rBbKI group.

	SAL	ELA	SAL-rBbKI	ELA-rBbKI
Inflammatory markers
Neutrophils (cells/10^4 μm^2)
TNF-α (cells/10^4 μm^2)
Remodeling markers
Collagen fibers (%)
Elastic fibers (%)
MMP-9 (cells/10^4 μm^2)
MMP-12 (cells/10^4 μm^2)
TIMP-1 (cells/10^4 μm^2)
Oxidative stress markers
iNOS (cells/10^4 μm^2)
eNOS (cells/10^4 μm^2)
8-iso-PGF2α (%)
Mucus production
MUC-5 (cells/10^4 μm^2)