Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21

<div>Metformin increased brown fat gene expression and function. (a) Oil Red O staining in metformin (5 mM) or metformin plus anti-FGF21-treated 3T3L1 cells. (b and c) Relative gene expression associated with (b) white adipose tissue (WAT) and (c) brown adipose tissue (BAT). Data represent means ± SEM.</div>

Mediators of Inflammation

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Figure 5

Figure 5: Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21 