Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment

Figure 1

Differentiation of tumor-associated myeloid cells begins from hematopoietic stem cells (HSC) in the bone marrow. CMP: common myeloid progenitors, IMC: immature myeloid cells, TEM: Tie2-expressing monocyte, MDSC: myeloid-derived suppressor cell, M-MDSC: myeloid MDSC, G-MDSC: granulocytic MDSC, iDC: immature dendritic cells, TADC: tumor-associated dendritic cells, TAM: tumor-associated macrophage, and TAN: tumor-associated neutrophil [63].