Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

Figure 4

Th17 response was enhanced by blocking the Wnt/β-catenin pathway. (a) The percentage of IL-17A⁺CD4⁺ T cells in HLN was calculated by flow cytometry; data were shown as scatter plot and graph. Expressions of IL-17A (b), IL-6 (c), and IL-23 (d) in lung were assayed by real-time RT-PCR using the method. Values are shown as mean ± SEM (-5) (, as compared with saline group at the same time point, ; #, as compared with silica group and silica + NC shRNA group at the same time point, ).

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