Pancreatic Acinar Cells Employ miRNAs as Mediators of Intercellular Communication to Participate in the Regulation of Pancreatitis-Associated Macrophage Activation

Figure 2

The microarray analysis of the exosomal miRNAs isolated from the culture medium of rat pancreatic acinar cells. (a) Microscopic images of cultured rat pancreatic acinar cells-AR42J cells. (b) MTT assay for detection of cell viability of AR42J cells; there is no significant difference between the two groups, . (c) Laser confocal microscopic images of AR42J cells labelled by BZiPAR for assessing intracellular trypsinogen activation. (d) Microarray hybridization profiles of exosomal miRNAs isolated from the culture medium of AR42J cells. (e) Cluster analysis diagram. Green denotes miRNAs expressed at low levels in the corresponding samples, whereas red denotes the miRNAs expressed at high levels in the corresponding samples.

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