Research Article

Linking CD11b+ Dendritic Cells and Natural Killer T Cells to Plaque Inflammation in Atherosclerosis

Table 3

Spearman’s rank correlation coefficients () of associations between gene expression results within plaques or between plaques and circulating NKT cells or CD11b+ cDC.

6 wk of WD
T-betCCR5CCR7Vα14-Jα18Zbtb46SIRPαXCR1Stenosis

T-bet0.9000.7000.200−0.200−0.4000.9000.354
Stenosis0.3540.3540.7070.7070.7550.7550.354
Vα14-Jα180.2000.5000.3000.4000.2000.5000.707
NKT cells−1.000−0.800−1.000−0.400−1.000−0.500−0.800−0.657
CD11b+ DC−0.4000.000−0.1000.5000.0000.0000.000−0.251

12 wk of WD
T-betCCR5CCR7Vα14-Jα18Zbtb46SIRPαXCR1Stenosis

T-bet0.8550.8550.8910.758−0.8180.952−0.261
Stenosis−0.261−0.515−0.393−0.370−0.3810.345−0.200
Vα14-Jα180.8910.7210.8790.636−0.8300.939−0.370
NKT cells−0.456−0.535−0.426−0.322−0.1160.274−0.377−0.189
CD11b+ DC−0.717−0.733−0.717−0.583−0.6500.633−0.7330.400

p, plaque; b, blood.
The magnitude of the correlation coefficient determines the strength of the correlation: || > 0.7 strong correlation; 0.5 < || < 0.7 moderate correlation; || < 0.5 weak correlation.