Linking CD11b+ Dendritic Cells and Natural Killer T Cells to Plaque Inflammation in Atherosclerosis
Table 3
Spearman’s rank correlation coefficients () of associations between gene expression results within plaques or between plaques and circulating NKT cells or CD11b+ cDC.
6 wk of WD
T-bet
CCR5
CCR7
Vα14-Jα18
Zbtb46
SIRPα
XCR1
Stenosis
T-bet
—
0.900
0.700
0.200
−0.200
−0.400
0.900
0.354
Stenosis
0.354
0.354
0.707
0.707
0.755
0.755
0.354
—
Vα14-Jα18
0.200
0.500
0.300
—
0.400
0.200
0.500
0.707
NKT cells
−1.000
−0.800
−1.000
−0.400
−1.000
−0.500
−0.800
−0.657
CD11b+ DC
−0.400
0.000
−0.100
0.500
0.000
0.000
0.000
−0.251
12 wk of WD
T-bet
CCR5
CCR7
Vα14-Jα18
Zbtb46
SIRPα
XCR1
Stenosis
T-bet
—
0.855
0.855
0.891
0.758
−0.818
0.952
−0.261
Stenosis
−0.261
−0.515
−0.393
−0.370
−0.381
0.345
−0.200
—
Vα14-Jα18
0.891
0.721
0.879
—
0.636
−0.830
0.939
−0.370
NKT cells
−0.456
−0.535
−0.426
−0.322
−0.116
0.274
−0.377
−0.189
CD11b+ DC
−0.717
−0.733
−0.717
−0.583
−0.650
0.633
−0.733
0.400
p, plaque; b, blood. The magnitude of the correlation coefficient determines the strength of the correlation: || > 0.7 strong correlation; 0.5 < || < 0.7 moderate correlation; || < 0.5 weak correlation.