2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis

Figure 5

THSG attenuated ligature-induced experimental periodontitis. Rats were performed ligature-induced experimental periodontitis at first molar and fed with THSG (0.1 or 10 mg/kg/day dissolved in sterile water) or sterile water by gavage for 7 days. (a) The alveolar bone crest (white arrow) and the cementoenamel junction (CEJ, white arrowhead) were shown on radiographic images of the mandible from these treatments. (b) The radiographic lost alveolar bone level was measured along the mesial/distal root surface and was defined as the distance from the CEJ to the most coronal level of the alveolar bone crest. ( was compared with control group. ; were compared with 0 mg/kg THSG group.)

(a)

(b)