2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis

Figure 7

P. Multiflori ethanol extracts attenuated ligature-induced experimental periodontitis. Rats were performed ligature-induced experimental periodontitis at first molar and then fed with resveratrol (25 mg/kg/day dissolved in 50% ethanol), ethanol extracts (12.5, 25, or 50 mg/kg/day dissolved in 50% ethanol), or 50% ethanol by gavage for 7 days. (a) The periodontal bone-supporting ratio was measured along the distal root surface and was labeled (based on measurements spanning the cusp tip, E, the deepest bony defect, A, and the root apex, R) as the A-R distance divided by the E-R distance 100%. (b) The periodontal bone-supporting ratio was measured and shown. (; ; were compared with control group. ; ; were compared with ligature group.)

(a)

(b)