Research Article

Differential Expression of Inflammation-Related Genes in Children with Down Syndrome

Table 2

Significantly different gene expression between children with and without DS.

GeneGene IDGene nameMean RQRQ value

BDKRB1623Bradykinin receptor B1 0.0013−9.62250.0003
LTA4H4048Leukotriene A4 hydrolase0.0079−6.98990.0005
ITGAM3684Integrin, alpha-M (complement component 3 receptor 3 subunit)0.0364−4.78110.0144
ADRB2154Adrenoceptor beta 2, surface0.0543−4.20370.0089
CD40LG959CD40 ligand0.0737−3.76130.0151
ITGB13688Integrin, beta 10.0779−3.68220.0399
TNFRSF1B7133Tumor necrosis factor receptor superfamily, member 1B0.0829−3.59170.0258
TBXAS16916Thromboxane A synthase 1 (platelet)0.1032−3.27680.0428
PLCB45332Phospholipase C, beta 48.76763.13220.0443
ICAM13383Intercellular adhesion molecule 19.71163.27970.0268
HTR3A33595-Hydroxytryptamine (serotonin) receptor 3A, ionotropic9.83193.29750.0343
ALOX12239Arachidonate 12-lipoxygenase10.61983.40870.0171
PLA2G55322Phospholipase A2, group V12.56883.65180.0423
PDE4C5143Phosphodiesterase 4C, cAMP-specific19.29274.27000.0390
PLCD15333Phospholipase C, delta 119.95104.31840.0449
PLA2G2D26279Phospholipase A2, group IID21.39144.41900.0067
ADRB1153Adrenoceptor beta 124.22354.59830.0491
CACNA1D776Calcium channel, voltage-dependent, L type, alpha 1D subunit25.30554.66140.0125
CASP1834Caspase 1, apoptosis-related cysteine peptidase47.14215.55890.0479
VCAM17412Vascular cell adhesion molecule 152.88855.72490.0243

Gene Identification second-base gene data, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov/gene).