Research Article
Differential Expression of Inflammation-Related Genes in Children with Down Syndrome
Table 2
Significantly different gene expression between children with and without DS.
| Gene | Gene ID | Gene name | Mean RQ | RQ | value |
| BDKRB1 | 623 | Bradykinin receptor B1 |
0.0013 | −9.6225 | 0.0003 | LTA4H | 4048 | Leukotriene A4 hydrolase | 0.0079 | −6.9899 | 0.0005 | ITGAM | 3684 | Integrin, alpha-M (complement component 3 receptor 3 subunit) | 0.0364 | −4.7811 | 0.0144 | ADRB2 | 154 | Adrenoceptor beta 2, surface | 0.0543 | −4.2037 | 0.0089 | CD40LG | 959 | CD40 ligand | 0.0737 | −3.7613 | 0.0151 | ITGB1 | 3688 | Integrin, beta 1 | 0.0779 | −3.6822 | 0.0399 | TNFRSF1B | 7133 | Tumor necrosis factor receptor superfamily, member 1B | 0.0829 | −3.5917 | 0.0258 | TBXAS1 | 6916 | Thromboxane A synthase 1 (platelet) | 0.1032 | −3.2768 | 0.0428 | PLCB4 | 5332 | Phospholipase C, beta 4 | 8.7676 | 3.1322 | 0.0443 | ICAM1 | 3383 | Intercellular adhesion molecule 1 | 9.7116 | 3.2797 | 0.0268 | HTR3A | 3359 | 5-Hydroxytryptamine (serotonin) receptor 3A, ionotropic | 9.8319 | 3.2975 | 0.0343 | ALOX12 | 239 | Arachidonate 12-lipoxygenase | 10.6198 | 3.4087 | 0.0171 | PLA2G5 | 5322 | Phospholipase A2, group V | 12.5688 | 3.6518 | 0.0423 | PDE4C | 5143 | Phosphodiesterase 4C, cAMP-specific | 19.2927 | 4.2700 | 0.0390 | PLCD1 | 5333 | Phospholipase C, delta 1 | 19.9510 | 4.3184 | 0.0449 | PLA2G2D | 26279 | Phospholipase A2, group IID | 21.3914 | 4.4190 | 0.0067 | ADRB1 | 153 | Adrenoceptor beta 1 | 24.2235 | 4.5983 | 0.0491 | CACNA1D | 776 | Calcium channel, voltage-dependent, L type, alpha 1D subunit | 25.3055 | 4.6614 | 0.0125 | CASP1 | 834 | Caspase 1, apoptosis-related cysteine peptidase | 47.1421 | 5.5589 | 0.0479 | VCAM1 | 7412 | Vascular cell adhesion molecule 1 | 52.8885 | 5.7249 | 0.0243 |
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Gene Identification second-base gene data, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov/gene).
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