NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-κB Signaling Pathway

Figure 5

Effect of NBD on SOD and T-AOC activity and MDA concentrations in the lung tissues of mice with ALI. LPS challenge significantly increased MDA levels and decreased SOD and T-AOC activity compared with sham controls; however, treatment with the middle and large NBD concentrations exerted effects contrasting with those described above. Data are expressed as the mean ± SD (n = 6). represents versus control group, < 0.05; represents versus model group, < 0.05; represents versus N-NBD group, < 0.05; represents versus NBD-2 group, < 0.05.

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