mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections

Figure 5

ROS production in monocytes. There was significantly higher ROS production in monocytes from TSC1 KO mice (CD11b⁺Ly6c⁺) than from WT mice. The difference was attenuated in monocytes with the Rapa treatment (1.5 mg/kg, four days before treatment) (four mice per group, three representative experiments). compared to WT mice or between the indicated groups. values were determined using Student’s -tests.