Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy

<div>ASPP2 expression in PVR membranes. Fluorescence micrograph showing colocalization of ASPP2 (red) and cytokeratin (green) in both PVR membranes and ERM. Cell nuclei were stained with DAPI (blue). Isotype IgG was used for the negative control. Representative results obtained from samples of patients number 1 and number 10 are shown. PVR, proliferative vitreoretinopathy; ERM, epiretinal membranes; DAPI, 4′,6′-diamino-2-phenylindole. Scale bars, 100 <i>μ</i>m.</div>

Mediators of Inflammation

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Figure 1

Figure 1: Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy 