Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study
Table 3
Sequences and locations of NF-κB1 putative binding sites within the regulatory region of intercellular adhesion molecule 1 (ICAM-1). For the purposes of this study, the ICAM-1 regulatory region was defined as 5000 bp of sequence immediately upstream of the ICAM-1 gene transcription start site and the first 2 introns. Gene sequences were obtained from the JASPAR database [21].
