Hydroxysafflor Yellow A Inhibits LPS-Induced NLRP3 Inflammasome Activation via Binding to Xanthine Oxidase in Mouse RAW264.7 Macrophages

Figure 2

XO is a potential target of HSYA via PharmMapper inverse docking. 300 potential candidates out of 7302 were listed and sorted according to the fit score. The molecule and pharmacophore model of XO (PDB ID: 1F04) was exhibited right below the selected target. Note: pharmacophore features are schemed by color: hydrophobic, cyan; positive, blue; negative, red; donor, green; acceptor, magenta.