Infusion of Hibiscus sabdariffa L. Modulates Oxidative Stress in Patients with Marfan Syndrome

Table 1

Demographics general and characteristics of the Marfan syndrome patients.

Number	Gender	Age	Time course of the disease	Family history	Lens dislocation	Systemic score	Aortic diameter (mm)	-score	Dissection	Mutation gen
1	F	58	4	+	−	8/20	68		+	FBN-1 and TGFBR2 negative
2	F	23	6	+	−	10/20	33		No data	FBN-1 and TGFBR2 negative
3	M	12	9	+	+	9/20	32	3.79	No data	FBN-1 positive, 42 exons
4	M	10	6	+	+	10/20	35	4.7	No data	FBN-1 positive, 14 exons
5	M	57	12	+	+	7/20	70		+	FBN-1 positive, 42 and 28 exons
6	M	57	4	+	−	9/20	58		No data	FBN-1 negative and TGFBR2
7	M	23	2	−	+	7/20	91		+	FBN-1 positive, 28 exons
8	M	58	2	−	+	7/20	68		+	—
9	M	28	6	+	−	9/20	70		−	FBN-1 positive, 14 exons
10	M	37	3	−	−	7/20	55		−	FBN-1 positive, 14 exons
11	M	46	20	+	+	7/20	80		−	FBN-1 positive, 42 exons
12	M	32	13	−	−	9/20	38		−	—
13	M	12	4	+	−	7/20	30	3.04	−	TGFBR2 positive, 6 exons
14	F	17	4	+	−	6/20	26	1.05	−	TGFBR2 positive, 6 exons
15	F	16	4	+	−	7/20	49	6.42	−	TGFBR2 positive, 6 exons
16	M	12	4	+	−	9/20	35	4.42	−	FBN-1 and TGFBR2 negative
17	F	22	4	+	−	7/20	57		+	FBN-1 positive, 14 exons and positive TGFBR2, 6 exons

F = female and M = male. -score was adjusting the measure aortic diameter age and weight.